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Article

Role of beta-catenin in B cell development and function.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2008

Yu Qing, Quinn William J, Salay Theresa, Crowley Jenni E, Cancro Michael P, Sen Jyoti Misra

Abstract excerpt

beta-Catenin is a central mediator of Wnt signaling pathway, components of which have been implicated in B cell development and function. B cell progenitors and bone marrow stromal cells express Wnt ligands, Frizzled receptors and Wnt antagonists, suggesting fine tuned regulation of this pathway in B cell development. In particular, deletion of Frizzled 9 gene results in developmental defects at the pre-B stage...

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Identifiers

PMID: 18768830
DOI: 10.4049/jimmunol.181.6.3777
PMCID: PMC2575415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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