Article
Genetic polymorphisms of the E-cadherin promoter and risk of sporadic gastric carcinoma in Chinese populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2008
Zhang Baozhen, Pan Kaifeng, Liu Zhaojun, Zhou Jing, Gu Liankun, Ji Jiafu, Ma Junling, You Wei-cheng, Deng Dajun
Abstract excerpt
Frequent mutations and loss of expression of E-cadherin have been reported in a number of cancers. E-cadherin germ line mutations lead to a high risk of familial diffused gastric carcinoma. In the present study, to evaluate the effect of genetic polymorphisms in the E-cadherin promoter on the risk of sporadic gastric carcinoma (SGC), a comprehensive study was conducted in two populations with high and low risk of...
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