Article
The E-cadherin (CDH1) -160C>A polymorphism associated with gastric cancer among Asians but not Europeans.
DNA and cell biology - 1 Jun 2011
Wang Qiong, Gu Dongying, Wang Meilin, Zhang Zhengdong, Tang Jinhai, Chen Jinfei
Abstract excerpt
E-cadherin (CDH1) is a tumor suppressor gene involved in epithelial cell-cell interactions and plays important roles in the etiology of gastric cancer. Studies reporting conflicting results on the role of -160C>A polymorphism in the CDH1 promoter region on gastric cancer risk led us to perform a meta-analysis to investigate this relationship. Thirteen published case-control studies including 2509 gastric cancer...
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