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Article

The E-cadherin -347G->GA promoter polymorphism and its effect on transcriptional regulation.

Carcinogenesis - 1 Jun 2004

Shin Yong, Kim Il-Jin, Kang Hio Chung, Park Jae-Hyun, Park Hye-Rin, Park Hye-Won, Park Mi Ae, Lee Jong Soo, Yoon Kyong-Ah, Ku Ja-Lok, Park Jae-Gahb

Abstract excerpt

E-cadherin plays a critical role in epithelial cell-cell adhesion and maintenance of tissue architecture. Loss of E-cadherin expression in humans has been associated with cancer, and a number of cancer-related mutations have been identified. Here, we sought to investigate whether the -347G-->GA single nucleotide polymorphism affects the transcriptional activity of the E-cadherin gene. First, we measured the...

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PMID: 14729585
DOI: 10.1093/carcin/bgh073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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