Article
Association of the -160 C --> a promoter polymorphism of E-cadherin gene with gastric carcinoma risk.
Cancer - 1 Mar 2002
Wu Ming-Shiang, Huang Shih-Pei, Chang Yu-Ting, Lin Ming-Tsan, Shun Chia-Tung, Chang Ming-Chu, Wang Hsiu-Po, Chen Chien-Jen, Lin Jaw-Town
Abstract excerpt
BACKGROUND: A -160 C --> A polymorphism in the promoter region of E-cadherin has been shown to decrease gene transcription. This allelic variation might be a potential genetic marker for identifying individuals at risk for cancer. There remains no report regarding the polymorphism of E-cadherin in gastric carcinoma (GC). METHODS: A hospital-based case-control study, including 201 GC cases and 196 unaffected...
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