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Article

Meta-analysis of Mendelian randomization studies incorporating all three genotypes.

Statistics in medicine - 30 Dec 2008

Palmer Tom M, Thompson John R, Tobin Martin D

Abstract excerpt

In Mendelian randomization a carefully selected gene is used as an instrumental variable in the estimation of the association between a biological phenotype and a disease. A study using Mendelian randomization will have information on an individual's disease status, the genotype and the phenotype. The phenotype must be on the causal pathway between gene and disease for the instrumental-variable analysis to be...

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PMID: 18767201
DOI: 10.1002/sim.3423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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