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Article

Insight into rheumatological cause and effect through the use of Mendelian randomization.

Nature reviews. Rheumatology - 1 Aug 2016

Robinson Philip C, Choi Hyon K, Do Ron, Merriman Tony R

Abstract excerpt

Establishing causality of risk factors is important to determine the pathogenetic mechanisms underlying rheumatic diseases, and can facilitate the design of interventions to improve care for affected patients. The presence of unmeasured confounders, as well as reverse causation, is a challenge to the assignment of causality in observational studies. Alleles for genetic variants are randomly inherited at meiosis....

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Identifiers

PMID: 27411906
DOI: 10.1038/nrrheum.2016.102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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