Article
Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.
Archives of general psychiatry - 1 Sept 2008
van den Oord Edwin J C G, Kuo Po-Hsiu, Hartmann Annette M, Webb B Todd, Möller Hans-Jürgen, Hettema John M, Giegling Ina, Bukszár József, Rujescu Dan
Abstract excerpt
CONTEXT: Neuroticism is a trait that reflects a tendency toward negative mood states. It has long been linked to internalizing psychiatric conditions, such as anxiety and depression, and it accounts for much of the substantial comorbidity seen between these disorders. OBJECTIVE: To identify common genetic variants that affect neuroticism to better understand (the comorbidity between) a broad range of psychiatric...
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