Article
Protective role of interlekin-1 alpha gene polymorphism in Chinese Han population with sporadic Parkinson's disease.
Neuroscience letters - 7 Nov 2008
Zhou Yong-tao, Yang Jin-fang, Zhang Yan-li, Wang Xing-yu, Chan Piu
Abstract excerpt
Parkinson's disease is the second most common neurodegenerative disorders after Alzheimer's disease in the elderly. Abundant evidence showed that proinflammatory factors were involved in the pathogenesis of sporadic Parkinson's disease (SPD). Interleukin-1 (IL-1) is a cytokine that plays an important role in neurodegenerative disease. Previous association studies between genetic polymorphisms of IL-1 alpha and PD...
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