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Article

Polymorphisms in the interleukin-1 alpha and beta genes and the risk for Parkinson's disease.

Neuroscience letters - 21 Jun 2002

Schulte Thorsten, Schöls Ludger, Müller Thomas, Woitalla Dirk, Berger Klaus, Krüger Rejko

Abstract excerpt

Several lines of evidence indicate that immune mechanisms are involved in the pathogenesis of neurodegenerative disorders. Activated immunocompetent cells and inflammatory cytokines are present in affected brain regions in patients with Alzheimer's (AD) and Parkinson's disease (PD). For AD biochemical and pathological data are supported by genetic studies identifying risk alleles for polymorphisms in regulatory...

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PMID: 12052541
DOI: 10.1016/s0304-3940(02)00301-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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