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Article

Association of interleukin-1 beta polymorphisms with idiopathic Parkinson's disease.

Neuroscience letters - 21 Jun 2002

McGeer Patrick L, Yasojima Koji, McGeer Edith G

Abstract excerpt

Activated microglia surround degenerating substantia nigra neurons in Parkinson's disease (PD). Such microglia produce high levels of interleukin-1 beta (IL-1 beta) and interleukin-1 alpha (IL-1 alpha). T and C alleles exist for the IL-1 beta-511 regulatory region as well as for the IL-1 alpha-889 regulatory region. The T genotypes of both have been reported to increase the risk of Alzheimer's disease (AD) (Arch....

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PMID: 12052540
DOI: 10.1016/s0304-3940(02)00300-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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