Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor necrosis factor-alpha promoter polymorphism is associated with the risk of Parkinson's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2007

Wu Yih-Ru, Feng I-Hsin, Lyu Rong-Kuo, Chang Kuo-Hsuan, Lin Yu-Yun, Chan Huiling, Hu Fen-Ju, Lee-Chen Guey-Jen, Chen Chiung-Mei

Abstract excerpt

Inflammatory events may contribute to the pathogenesis of Parkinson's disease (PD). We conducted a case-control study in a cohort of 369 PD cases and another cohort of 326 ethnically matched controls to investigate the association of tumor necrosis factor-alpha (TNF-alpha) promoter single nucleotide polymorphisms (SNPs) with the risk of PD. The overall genotype distribution at T-1031C and C-857T sites showed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Linkage

Share to Haplotypes

Share to Parkinson Disease

Share to Promoter Regions, Genetic

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 17192953
DOI: 10.1002/ajmg.b.30435

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor necrosis factor-alpha promoter polymorphism is associated with the risk of Parkinson's disease.PMID 17192953Read ↗

Tumor necrosis factor gene polymorphisms in patients with sporadic Parkinson's disease.Semantic proximity Read ↗

Inflammation-related gene polymorphisms associated with Parkinson’s disease: an updated meta-analysisSemantic proximity Read ↗

Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease.Semantic proximity Read ↗

Interleukin-1 alpha polymorphism has influence on late-onset sporadic Parkinson's disease in Taiwan.Semantic proximity Read ↗

TNF-α -308 G/A and -238 G/A promoter polymorphisms and sporadic Parkinson's disease in an Italian cohort.Semantic proximity Read ↗

Protective role of interlekin-1 alpha gene polymorphism in Chinese Han population with sporadic Parkinson's disease.Semantic proximity Read ↗

Interleukin-10 (IL10) and tumor necrosis factor alpha (TNF) gene polymorphisms in Parkinson's disease patients.Semantic proximity Read ↗

Interleukin-10 promoter polymorphisms in Chinese patients with Parkinson's disease.Semantic proximity Read ↗

Cytokine gene polymorphisms and Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in immune/inflammatory cytokine genes are related to Parkinson's disease with cognitive impairment in the Han Chinese population.Semantic proximity Read ↗

Interleukin-18 promoter polymorphisms and risk of Parkinson's disease in a Han Chinese population.Semantic proximity Read ↗

Investigation of genes coding for inflammatory components in Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.