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Article

Interleukin-18 promoter polymorphisms and idiopathic Parkinson disease: an Egyptian study.

Acta neurologica Belgica - 1 Jun 2019

Fahmy Ebtesam, Rabah Amany, Sharaf Sahar, Helmy Hanan, Kamal Ahmed

Abstract excerpt

Etiology of sporadic Parkinson's disease (PD) is largely unknown. The contribution of genetic factors to the pathogenesis of PD is supported by the demonstration of high concordance in twins, increased risk among relatives of PD patients and existence of familial cases. This study aimed to examine the relation between interleukin 18 (IL-18) gene promoter polymorphisms and idiopathic PD, and its impact on clinical...

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PMID: 29700781
DOI: 10.1007/s13760-018-0927-7

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