Article
Gene expression regulation in the context of mouse interspecific mosaic genomes.
Genome biology - 1 Jan 2008
L'Hôte David, Serres Catherine, Veitia Reiner A, Montagutelli Xavier, Oulmouden Ahmad, Vaiman Daniel
Abstract excerpt
BACKGROUND: Accumulating evidence points to the mosaic nature of the mouse genome. However, little is known about the way the introgressed segments are regulated within the context of the recipient genetic background. To address this question, we have screened the testis transcriptome of interspecific recombinant congenic mouse strains (IRCSs) containing segments of Mus spretus origin at a homozygous state in a...
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