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Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression.

Experimental animals - 9 Jul 2024

Saito Ayaka, Tahara Ryosuke, Hirose Michiko, Kadota Masayo, Hasegawa Ayumi, Kondo Shinji, Kato Hidemasa, Amano Takanori, Yoshiki Atsushi, Ogura Atsuo, Kiyosawa Hidenori

Abstract excerpt

Allele-specific monoallelic gene expression is a unique phenomenon and a great resource for analyzing gene regulation. To study this phenomenon, we established new embryonic stem (ES) cell lines derived from F1 hybrid blastocysts from crosses between four mouse subspecies (Mus musculus domesticus, C57BL/6; M. musculus molossinus, MSM/Ms; M. musculus musculus, PWK; M. musculus castaneus, HMI/Ms) and analyzed the...

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Identifiers

PMID: 38447983
DOI: 10.1538/expanim.24-0002
PMCID: PMC11254486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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