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Article

Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila.

Genetics - 1 Dec 2005

Landry Christian R, Wittkopp Patricia J, Taubes Clifford H, Ranz Jose M, Clark Andrew G, Hartl Daniel L

Abstract excerpt

Hybrids between species are often characterized by novel gene-expression patterns. A recent study on allele-specific gene expression in hybrids between species of Drosophila revealed cases in which cis- and trans-regulatory elements within species had coevolved in such a way that changes in cis-regulatory elements are compensated by changes in trans-regulatory elements. We hypothesized that such coevolution...

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Identifiers

PMID: 16143608
DOI: 10.1534/genetics.105.047449
PMCID: PMC1456106

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