Article
A novel epigenetic control operating on Vme1+ locus leads to variegated monoallelic expression.
Biochemical and biophysical research communications - 29 Dec 2000
Jeong S, Lee Y J, Jang J S, Park C W, Chung J H, Seong J K, Lee K K, Yu D Y
Abstract excerpt
Vme1, located near an imprinted region containing Peg1/Mest, Copg2, and Mit1/Lb9 on mouse chromosome 6, was identified and characterized to be under novel epigenetic regulations mediating nonimprinted monoallelic expression. The gene was transcribed independently from at least four promoters and alternatively spliced. Variable expression of the gene was found among individuals and was not affected by genetic...
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