Immunoaffinity-purified DNA polymerase alpha from a mouse temperature-sensitive mutant, tsFT20 strain, is heat-labile.

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Article

Immunoaffinity-purified DNA polymerase alpha from a mouse temperature-sensitive mutant, tsFT20 strain, is heat-labile.

The Journal of biological chemistry - 25 Aug 1991

Takada-Takayama R, Hanaoka F, Yamada M, Ui M

Abstract excerpt

We have purified DNA polymerase alpha from a temperature-sensitive mutant cell line of mouse FM3A cells, tsFT20, that shows temperature-sensitive activity of DNA polymerase alpha (Murakami, Y., Yasuda, H., Miyazawa, H., Hanaoka, F., and Yamada, M. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 1761-176...

Topics

Animals
Chromatography, Affinity
DNA Polymerase II
DNA Primase
Electrophoresis, Polyacrylamide Gel
Hot Temperature
Mice
Molecular Weight
Mutation
RNA Nucleotidyltransferases
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1874729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1874729-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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