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Article

aex-3 encodes a novel regulator of presynaptic activity in C. elegans.

Neuron - 1 Apr 1997

Iwasaki K, Staunton J, Saifee O, Nonet M, Thomas J H

Abstract excerpt

C. elegans aex-3 mutations cause pleiotropic behavioral defects that are suggestive of reduced synaptic transmission. aex-3 mutations also show strong genetic interactions with mutations in unc-31 and unc-64, two other genes implicated in synaptic transmission. Physiological and pharmacological studies indicate that aex-3 defects are presynaptic. In aex-3 mutants, the synaptic vesicle-associated RAB-3 protein...

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PMID: 9136770
DOI: 10.1016/s0896-6273(00)80302-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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