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Article

Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans.

Molecular biology of the cell - 1 Jun 2006

Mahoney Timothy R, Liu Qiang, Itoh Takashi, Luo Shuo, Hadwiger Gayla, Vincent Rose, Wang Zhao-Wen, Fukuda Mitsunori, Nonet Michael L

Abstract excerpt

Rab small GTPases are involved in the transport of vesicles between different membranous organelles. RAB-3 is an exocytic Rab that plays a modulatory role in synaptic transmission. Unexpectedly, mutations in the Caenorhabditis elegans RAB-3 exchange factor homologue, aex-3, cause a more severe synaptic transmission defect as well as a defecation defect not seen in rab-3 mutants. We hypothesized that AEX-3 may...

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Identifiers

PMID: 16571673
DOI: 10.1091/mbc.e05-12-1170
PMCID: PMC1474797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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