Article
Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates.
BMC medical genetics - 12 Jan 2005
McCauley Jacob L, Li Chun, Jiang Lan, Olson Lana M, Crockett Genea, Gainer Kimberly, Folstein Susan E, Haines Jonathan L, Sutcliffe James S
Abstract excerpt
BACKGROUND: Autism is a neurobehavioral spectrum of phenotypes characterized by deficits in the development of language and social relationships and patterns of repetitive, rigid and compulsive behaviors. Twin and family studies point to a significant genetic etiology, and several groups have performed genomic linkage screens to identify susceptibility loci. METHODS: We performed a genome-wide linkage screen in...
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