Article
An association study of 21 potential Alzheimer's disease risk genes in a Finnish population.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Sarajärvi Timo, Helisalmi Seppo, Antikainen Leila, Mäkinen Petra, Koivisto Anne Maria, Herukka Sanna-Kaisa, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko
Abstract excerpt
Alzheimer's disease (AD) is a genetically complex disorder encompassing several individual susceptibility genes with low risk effects. To assess the risk gene effects in a cohort consisting of ∼ 1300 Finnish AD patients and controls, 21 candidate gene polymorphisms were selected for genotyping on the basis of the meta-analyses retrieved from the AlzGene database. A significant genotype and allele association with...
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