Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study.

PloS one - 20 Aug 2008

Kivimäki Mika, Lawlor Debbie A, Smith George Davey, Kumari Meena, Donald Ann, Britton Annie, Casas Juan P, Shah Tina, Brunner Eric, Timpson Nicholas J, Halcox Julian P J, Miller Michelle A, Humphries Steve E, Deanfield John, Marmot Michael G, Hingorani Aroon D

Abstract excerpt

BACKGROUND: C-reactive protein (CRP), a marker of systemic inflammation, is associated with risk of coronary events and sub-clinical measures of atherosclerosis. Evidence in support of this link being causal would include an association robust to adjustments for confounders (multivariable standard regression analysis) and the association of CRP gene polymorphisms with atherosclerosis (Mendelian randomization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Diabetes Mellitus

Share to Diabetic Angiopathies

Share to Life Style

Share to Lipids

Share to Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 18714381
DOI: 10.1371/journal.pone.0003013
PMCID: PMC2507732

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study.PMID 18714381Read ↗

Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey.Semantic proximity Read ↗

Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events.Semantic proximity Read ↗

C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.Semantic proximity Read ↗

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.Semantic proximity Read ↗

Causal relationship between C-reactive protein and ischemic stroke caused by atherosclerosis: A Mendelian randomization study.Semantic proximity Read ↗

Association of the -757T>C polymorphism in the CRP gene with circulating C-reactive protein levels and carotid atherosclerosis.Semantic proximity Read ↗

Genetic determinants of C-reactive protein.Semantic proximity Read ↗

The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants.Semantic proximity Read ↗

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.Semantic proximity Read ↗

Association of common CRP gene variants with CRP levels and cardiovascular events.Semantic proximity Read ↗

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data.Semantic proximity Read ↗

High-Sensitive C-Reactive Protein: Universal Prognostic and Causative Biomarker in Heart Disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.