Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

doi:10.1001/jama.2009.954

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Article

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

JAMA - 1 Jul 2009

Elliott Paul, Chambers John C, Zhang Weihua, Clarke Robert, Hopewell Jemma C, Peden John F, Erdmann Jeanette, Braund Peter, Engert James C, Bennett Derrick, Coin Lachlan, Ashby Deborah, Tzoulaki Ioanna, Brown Ian J, Mt-Isa Shahrul, McCarthy Mark I, Peltonen Leena, Freimer Nelson B, Farrall Martin, Ruokonen Aimo, Hamsten Anders, Lim Noha, Froguel Philippe, Waterworth Dawn M, Vollenweider Peter, Waeber Gerard, Jarvelin Marjo-Riitta, Mooser Vincent, Scott James, Hall Alistair S, Schunkert Heribert, Anand Sonia S, Collins Rory, Samani Nilesh J, Watkins Hugh, Kooner Jaspal S

Abstract excerpt

CONTEXT: Plasma levels of C-reactive protein (CRP) are independently associated with risk of coronary heart disease, but whether CRP is causally associated with coronary heart disease or merely a marker of underlying atherosclerosis is uncertain. OBJECTIVE: To investigate association of genetic loci with CRP levels and risk of coronary heart disease. DESIGN, SETTING, AND PARTICIPANTS: We first carried out a...

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Identifiers

PMID: 19567438
DOI: 10.1001/jama.2009.954
PMCID: PMC2803020

Genes

CRP
APOE
LEPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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