Article
Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey.
Scandinavian journal of clinical and laboratory investigation - 1 Sept 2011
Kettunen Terhi, Eklund Carita, Kähönen Mika, Jula Antti, Päivä Hannu, Lyytikäinen Leo-Pekka, Hurme Mikko, Lehtimäki Terho
Abstract excerpt
BACKGROUND: C-reactive protein (CRP) is an inflammatory protein that may play a role in the pathogenesis of cardiovascular disease (CVD). However, its status as a causal risk factor is still controversial. CRP gene single nucleotide polymorphisms (SNPs) have been shown to associate with CRP concentration, but not convincingly with early atherosclerotic changes. OBJECTIVE: We assessed whether CRP genotypes or...
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