Article
Association of the -757T>C polymorphism in the CRP gene with circulating C-reactive protein levels and carotid atherosclerosis.
Thrombosis research - 1 Sept 2009
Ben Assayag Einor, Shenhar-Tsarfaty Shani, Bova Irena, Berliner Shlomo, Usher Sali, Peretz Hava, Shapira Itzhak, Bornstein Natan M
Abstract excerpt
INTRODUCTION: C-reactive protein (CRP) is an inflammatory protein that may play a role in the pathogenesis of atherosclerosis. CRP gene single nucleotide polymorphisms (SNPs) have been shown to be associated with CRP concentration; however, their independent effect on atherosclerosis has not been yet established. We aimed to determine whether the 5'-flanking -757T>C CRP gene polymorphism is associated with CRP...
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