Article
C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.
Lancet (London, England) - 3 Dec 2005
Timpson Nicholas J, Lawlor Debbie A, Harbord Roger M, Gaunt Tom R, Day Ian N M, Palmer Lyle J, Hattersley Andrew T, Ebrahim Shah, Lowe Gordon D O, Rumley Ann, Davey Smith George
Abstract excerpt
BACKGROUND: Circulating C-reactive protein (CRP) is associated with the metabolic syndrome and might be causally linked to it. Our aim was to generate estimates of the association between plasma CRP and metabolic syndrome phenotypes that were free from confounding and reverse causation, to assess the causal role of this protein. METHODS: We examined associations between serum CRP concentration and metabolic...
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