Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury.

Journal of leukocyte biology - 1 Dec 2008

Holt Michael P, Cheng LinLing, Ju Cynthia

Abstract excerpt

The role of macrophages in the pathogenesis of acetaminophen (APAP)-induced liver injury remains controversial, as it has been demonstrated that these cells display pro-toxicant and hepato-protective functions. This controversy may stem from the heterogeneity and/or plasticity of macrophages and the difficulty in distinguishing and differentially studying subpopulations of macrophages in the liver. In the present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetaminophen
Share to Analgesics, Non-Narcotic
Share to Bone Marrow

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Jurkat Cells

Share to Macrophages

Share to Necrosis

Share to Phagocytosis

Share to Receptors, CCR2

Source

Open in PubMed Open full text

Identifiers

PMID: 18713872
DOI: 10.1189/jlb.0308173
PMCID: PMC2614594

Genes

CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury.PMID 18713872Read ↗

The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liver injury.Semantic proximity Read ↗

Ambiguous Pathogenic Roles of Macrophages in Alcohol-Associated Liver DiseasesSemantic proximity Read ↗

Macrophages and Alcohol-Related Liver Inflammation.Semantic proximity Read ↗

Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice.Semantic proximity Read ↗

Macrophage Phenotype and Function in Liver Disorder.Semantic proximity Read ↗

Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure.Semantic proximity Read ↗

Adenosine A2B Receptor Activation: A Novel Therapeutic Strategy for Accelerating Liver Recovery After Acetaminophen OverdoseSemantic proximity Read ↗

Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis.Semantic proximity Read ↗

Macrophage heterogeneity in liver injury and fibrosisSemantic proximity Read ↗

High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype.Semantic proximity Read ↗

Phenotypic Characterization of Macrophages from Rat Kidney by Flow Cytometry.Semantic proximity Read ↗

CD36 deficiency ameliorates drug-induced acute liver injury in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.