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Article

Possible relationship between the risk of Japanese bladder cancer cases and the CYP4B1 genotype.

Japanese journal of clinical oncology - 1 Sept 2008

Sasaki Takamitsu, Horikawa Miho, Orikasa Kazuhiko, Sato Makoto, Arai Yoichi, Mitachi Yoshitaka, Mizugaki Michinao, Ishikawa Masaaki, Hiratsuka Masahiro

Abstract excerpt

Cytochrome P450 4B1 (CYP4B1) is involved in the metabolism of several xenobiotics, such as 2-aminofluorene, 2-naphthylamine and benzidine. CYP4B1 allelic variants CYP4B1*1-*7 were recently identified. We thus hypothesized that CYP4B1 genotypes may modify bladder cancer risk. We examined the CYP4B1 genotypes in 169 bladder cancer cases and 190 hospital controls using a hybridization probe assay. Among the CYP4B1...

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PMID: 18713828
DOI: 10.1093/jjco/hyn081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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