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An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China.

Toxicological sciences : an official journal of the Society of Toxicology - 1 May 2005

Lin Guo-Fang, Guo Wei-Chao, Chen Ji-Gang, Qin Yi-Qing, Golka Klaus, Xiang Cui-Qing, Ma Qing-Wen, Lu Da-Ru, Shen Jian-Hua

Abstract excerpt

UDP-Glucuronyltransferase 2B7 (UGT2B7) is involved in benzidine metabolism, as demonstrated by in vitro experiments with liver slices. To evaluate the possible association of UGT2B7 gene polymorphism with bladder cancer risk for benzidine-exposed subjects, diagnosed bladder cancer cases (n = 36) who were members of a cohort of benzidine-exposed workers in the Chinese dyestuff industry were investigated. UGT2B7...

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PMID: 15615884
DOI: 10.1093/toxsci/kfi068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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