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UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism in bladder cancer cases.

Journal of toxicology and environmental health. Part A - 1 Jan 2008

Zimmermann Anna, Blaszkewicz Meinolf, Roth Gerhard, Seidel Thilo, Dietrich Holger, Schutschkow Olga, Bolt Hermann M, Golka Klaus

Abstract excerpt

A study of Chinese benzidine workers indicated elevated levels of UDP-glucuronosyltransferase (UGT) 2B7 T/T activity in carriers for development of bladder cancer. The present study was designed to investigate the possible impact of the presence of UGT2B7 genotype on bladder cancer risk in Caucasians. UGT2B7 polymorphism at locus C(802)T (His(268)Tyr) was detected using a polymerase chain reaction-restriction...

Topics

Case-Control Studies
Genetic Predisposition to Disease
Genotype
Germany
Glucuronosyltransferase
Humans
Minor Histocompatibility Antigens
Odds Ratio
Polymorphism, Genetic
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Smoking

Urinary Bladder Neoplasms

White People

Source

Identifiers

PMID: 18569595
DOI: 10.1080/15287390801988772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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