Article
Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH.
Breast cancer research and treatment - 1 Aug 2009
Joosse Simon A, van Beers Erik H, Tielen Ivon H G, Horlings Hugo, Peterse Johannes L, Hoogerbrugge Nicoline, Ligtenberg Marjolijn J, Wessels Lodewyk F A, Axwijk Priscilla, Verhoef Senno, Hogervorst Frans B L, Nederlof Petra M
Abstract excerpt
BACKGROUND: While new defects in BRCA1 are still being found, it is unclear whether current breast cancer diagnostics misses many BRCA1-associated cases. A reliable test that is able to indicate the involvement of BRCA1 deficiency in cancer genesis could support decision making in genetic counselling and clinical management. To find BRCA1-specific markers and explore the effectiveness of the current diagnostic...
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