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Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers

4 Apr 2013

Abstract excerpt

BACKGROUND: BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its frequency in breast cancer is not known. Assays to establish BRCAness would be extremely valuable for the clinical management of these tumours. We assessed BRCAness characteristics frequencies in a large cohort of triple-negative breast cancers (TNBCs)....

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PMID: 23558900
DOI: 10.1038/bjc.2013.144

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