Article
Different Array CGH profiles within hereditary breast cancer tumors associated to BRCA1 expression and overall survival.
BMC cancer - 15 Mar 2016
Alvarez Carolina, Aravena Andrés, Tapia Teresa, Rozenblum Ester, Solís Luisa, Corvalán Alejandro, Camus Mauricio, Alvarez Manuel, Munroe David, Maass Alejandro, Carvallo Pilar
Abstract excerpt
BACKGROUND: Array CGH analysis of breast tumors has contributed to the identification of different genomic profiles in these tumors. Loss of DNA repair by BRCA1 functional deficiency in breast cancer has been proposed as a relevant contribution to breast cancer progression for tumors with no germline mutation. Identifying the genomic alterations taking place in BRCA1 not expressing tumors will lead us to a better...
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