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Article

Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729.

American journal of physiology. Cell physiology - 1 Oct 2008

Grenier Amy L, Abu-ihweij Khaled, Zhang Ge, Ruppert Shannon Moore, Boohaker Rebecca, Slepkov Emily R, Pridemore Kathryn, Ren Jian-Jian, Fliegel Larry, Khaled Annette R

Abstract excerpt

Apoptosis is a complex process essential for normal tissue development and cellular homeostasis. While biochemical events that occur late in the apoptotic process are better characterized, early physiological changes that initiate the progression of cell death remain poorly understood. Previously, we observed that lymphocytes, undergoing apoptosis in response to growth factor withdrawal, experienced a rapid and...

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Identifiers

PMID: 18701649
DOI: 10.1152/ajpcell.00574.2007
PMCID: PMC2575823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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