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Article

The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells

3 May 2018

Abstract excerpt

Precise acid-base homeostasis is essential for maintaining normal cell proliferation and growth. Conversely, dysregulated acid-base homeostasis, with increased acid extrusion and marked extracellular acidification, is an enabling feature of solid tumors, yet the mechanisms through which intra- and extracellular pH (pHi, pHe) impact proliferation and growth are incompletely understood. The aim of this study was to...

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PMID: 29895196
DOI: 10.1080/15384101.2018.1464850

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