Article
Fever-range hyperthermia improves the anti-apoptotic effect induced by low pH on human neutrophils promoting a proangiogenic profile.
Cell death & disease - 27 Oct 2016
Díaz Fernando Erra, Dantas Ezequiel, Cabrera Maia, Benítez Constanza A, Delpino María V, Duette Gabriel, Rubione Julia, Sanjuan Norberto, Trevani Analía S, Geffner Jorge
Abstract excerpt
Neutrophils have the shortest lifespan among leukocytes and usually die via apoptosis, limiting their deleterious potential. However, this tightly regulated cell death program can be modulated by pathogen-associated molecular patterns (PAMPs), danger-associated molecular pattern (DAMPs), and inflammatory cytokines. We have previously reported that low pH, a hallmark of inflammatory processes and solid tumors,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
