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Article

Genetic susceptibilities in the association between maternal exposure to tobacco smoke and the risk of nonsyndromic oral cleft.

American journal of medical genetics. Part A - 15 Sept 2008

Chevrier Cécile, Bahuau Michel, Perret Claire, Iovannisci David M, Nelva Agnès, Herman Christine, Vazquez Marie-Paule, Francannet Christine, Robert-Gnansia Elisabeth, Lammer Edward J, Cordier Sylvaine

Abstract excerpt

Maternal tobacco consumption is considered as a risk factor for nonsyndromic oral clefts. However, this risk is moderate and may be modulated by genetic susceptibilities, including variants of the TGFA, TGFB3 and MSX1 developmental genes and polymorphisms of genes of the CYP (1A1, 2E1) and GST (M...

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Source

Identifiers

PMID: 18698632
DOI: 10.1002/ajmg.a.32505

Genes

GSTT1
MSX1
GSTM1
TGFA
TGFB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18698632-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic susceptibilities in the association between maternal exposure to tobacco smoke and the risk of nonsyndromic oral cleft.PMID 18698632Read ↗

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