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Article

Stoichiometry of Kir channels with phosphatidylinositol bisphosphate.

Channels (Austin, Tex.) - 1 Jan 2000

Jin Taihao, Sui Jin Liang, Rosenhouse-Dantsker Avia, Chan Kim W, Jan Lily Y, Logothetis Diomedes E

Abstract excerpt

Phosphatidylinositol bisphosphate (PIP(2)) is the most abundant phosphoinositide in the plasma membrane of cells and its interaction with many ion channel proteins has proven to be a critical factor enabling ion channel gating. All members of the inwardly rectifying potassium (Kir) channel family depend on PIP(2) for their activity, displaying distinct affinities and stereospecificities of interaction with the...

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Source

Identifiers

PMID: 18690051
DOI: 10.4161/chan.2.1.5942

Genes

PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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