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Article

The RON receptor tyrosine kinase regulates IFN-gamma production and responses in innate immunity.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2008

Wilson Caleph B, Ray Manujendra, Lutz Michael, Sharda Daniel, Xu Jie, Hankey Pamela A

Abstract excerpt

Receptor tyrosine kinases are emerging as a class of key regulators of innate immune responses. We have shown previously that the RON receptor tyrosine kinases (murine Stk), expressed on tissue-resident macrophages, inhibit classical macrophage activation while promoting hallmarks of alternative activation, thus regulating the critical balance between the inflammatory and wound-healing properties of activated...

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Source

Identifiers

PMID: 18684919
DOI: 10.4049/jimmunol.181.4.2303

Genes

CIITA
STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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