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Article

MSP-RON Pathway: Potential Regulator of Inflammation and Innate Immunity

7 Oct 2020

Abstract excerpt

Macrophage-stimulating protein (MSP), a soluble protein mainly synthesized by the liver, is the only known ligand for recepteur d'origine nantais (RON), which is a member of the MET proto-oncogene family. Recent studies show that the MSP-RON signaling pathway not only was important in tumor behavior but also participates in the occurrence or development of many immune system diseases. Activation of RON in...

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PMID: 33117355
DOI: 10.3389/fimmu.2020.569082

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