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Article

TP53 gene mutations are rare in nondysplastic Barrett's esophagus.

Digestive diseases and sciences - 1 Jan 2006

Novotna Kamila, Trkova Marie, Pazdro Alexandr, Smejkal Milan, Soukupova Alzbeta, Kodetova Daniela, Smejkal Premysl, Sedlacek Zdenek

Abstract excerpt

In search of potential prognostic markers, we analyzed a large series of tissues of Barrett's esophagus and samples of adenocarcinomas arising in the terrain of Barrett's esophagus for TP53 gene mutations by direct sequencing of exons 5 to 9 of the TP53 gene. While 9 of 21 adenocarcinomas tested (42.9%) contained a TP53 mutation, none of 24 samples from Barrett's esophagus were mutated. This observation suggests...

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Source

Identifiers

PMID: 16416221
DOI: 10.1007/s10620-006-3093-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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