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Article

Clozapine-induced agranulocytosis and its genetic determinants.

Pharmacogenomics - 1 Aug 2008

Opgen-Rhein Carolin, Dettling Michael

Abstract excerpt

Clozapine-induced agranulocytosis (CiA) is a potentially life-threatening pharmacological adverse drug reaction, which limits a broader application of this highly effective atypical antipsychotic in schizophrenic patients. Although this adverse reaction has been well known for almost 30 years, only few genetically based determinants can be identified to date. Furthermore, owing to rare occurrence, specific...

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PMID: 18681784
DOI: 10.2217/14622416.9.8.1101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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