Article
Identification and characterisation of a nuclear localisation signal in the SMN associated protein, Gemin4.
Biochemical and biophysical research communications - 10 Oct 2008
Lorson Monique A, Dickson Alexa M, Shaw Debra J, Todd Adrian G, Young Elizabeth C, Morse Robert, Wolstencroft Catherine, Lorson Christian L, Young Philip J
Abstract excerpt
Gemin4 is a ubiquitously expressed multifunctional protein that is involved in U snRNP assembly, apoptosis, nuclear/cytoplasmic transportation, transcription, and RNAi pathways. Gemin4 is one of the core components of the Gemin-complex, which also contains survival motor neuron (SMN), the seven Gemin proteins (Gemin2-8), and Unrip. Mutations in the SMN1 gene cause the autosomal recessive disorder spinal muscular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.