Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gemin5, a Novel WD Repeat Protein Component of the SMN Complex That Binds Sm Proteins

1 Feb 2002

Abstract excerpt

The survival of motor neurons (SMN) protein is the product of the disease gene of spinal muscular atrophy and is found both in the cytoplasm and the nucleus, where it is concentrated in gems. SMN is part of a multi-protein complex that includes Gemin2, Gemin3, and Gemin4. The SMN complex plays an important role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs) and likely other RNPs in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenetic and Muscular Disorders Research
Share to RNA modifications and cancer
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11714716
DOI: 10.1074/jbc.m109448200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gemin5, a Novel WD Repeat Protein Component of the SMN Complex That Binds Sm ProteinsPMID 11714716Read ↗

Gemin4Semantic proximity Read ↗

Gemin8 Is a Novel Component of the Survival Motor Neuron Complex and Functions in Small Nuclear Ribonucleoprotein AssemblySemantic proximity Read ↗

Emerging Roles of Gemin5: From snRNPs Assembly to Translation ControlSemantic proximity Read ↗

Identification and Characterization of Gemin7, a Novel Component of the Survival of Motor Neuron ComplexSemantic proximity Read ↗

Gemin3Semantic proximity Read ↗

Gemins modulate the expression and activity of the SMN complexSemantic proximity Read ↗

Gemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN ExpressionSemantic proximity Read ↗

Multiprotein Complexes of the Survival of Motor Neuron Protein SMN with Gemins Traffic to Neuronal Processes and Growth Cones of Motor NeuronsSemantic proximity Read ↗

Composition of the Survival Motor Neuron (SMN) complex in <i>Drosophila melanogaster</i>Semantic proximity Read ↗

Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder.Semantic proximity Read ↗

Identification and characterisation of a nuclear localisation signal in the SMN associated protein, Gemin4.Semantic proximity Read ↗

<i>Gemin4</i> is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasmSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.