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Article

Gemin3

13 Dec 1999

Abstract excerpt

The survival of motor neurons (SMN) gene is the disease gene of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The SMN protein is part of a complex containing several proteins, of which one, SIP1 (SMN interacting protein 1), has been characterized so far. The SMN complex is found in both the cytoplasm and in the nucleus, where it is concentrated in bodies called gems. In the cytoplasm,...

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Identifiers

PMID: 10601333
DOI: 10.1083/jcb.147.6.1181

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