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Article

Gemin4

20 Mar 2000

Abstract excerpt

The survival of motor neurons (SMN) protein, the product of the neurodegenerative disease spinal muscular atrophy (SMA) gene, is localized both in the cytoplasm and in discrete nuclear bodies called gems. In both compartments SMN is part of a large complex that contains several proteins including Gemin2 (formerly SIP1) and the DEAD box protein Gemin3. In the cytoplasm, the SMN complex is associated with snRNP Sm...

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Identifiers

PMID: 10725331
DOI: 10.1083/jcb.148.6.1177

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