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Article

Synonymous and nonsynonymous polymorphisms versus divergences in bacterial genomes.

Molecular biology and evolution - 1 Oct 2008

Hughes Austin L, Friedman Robert, Rivailler Pierre, French Jeffrey O

Abstract excerpt

Comparison of the ratio of nonsynonymous to synonymous polymorphisms within species with the ratio of nonsynonymous to synonymous substitutions between species has been widely used as a supposed indicator of positive Darwinian selection, with the ratio of these 2 ratios being designated as a neutrality index (NI). Comparison of genome-wide polymorphism within 12 species of bacteria with divergence from an...

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Identifiers

PMID: 18667439
DOI: 10.1093/molbev/msn166
PMCID: PMC2734133

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