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Article

Nonsynonymous Polymorphism Counts in Bacterial Genomes: a Comparative Examination.

Applied and environmental microbiology - 17 Dec 2020

Loo Sara L, Ong Anna, Kyaw Wunna, Thibaut Loïc M, Lan Ruiting, Tanaka Mark M

Abstract excerpt

Genomic data reveal single-nucleotide polymorphisms (SNPs) that may carry information about the evolutionary history of bacteria. However, it remains unclear what inferences about selection can be made from genomic SNP data. Bacterial species are often sampled during epidemic outbreaks or within hosts during the course of chronic infections. SNPs obtained from genomic analysis of these data are not necessarily...

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PMID: 33097502
DOI: 10.1128/AEM.02002-20
PMCID: PMC7755258

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