Article
Predicting genetic and ecological characteristics of bacterial species by comparing the trajectories of dN/dS and dI/dS in bacterial genomes.
Molecular bioSystems - 1 Feb 2014
Feng Ye, Chiu Cheng-Hsun
Abstract excerpt
Indel (insertion/deletion) causes gene disruption and is considered to be deleterious like non-synonymous mutation during the evolution of bacterial genomes. The trajectory of dN/dS (the ratio of non-synonymous to synonymous mutation) has been found to decrease exponentially over time, but the trajectory of dI/dS (the ratio of indel to synonymous mutation) has not been thoroughly explored yet. Here we compared...
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